Anti-CBX3 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1117-YY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CBX3 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CBX3

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
11335

UniProt ID
Q13185

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1117-YY	CBYY-C1038	Mouse	Human		Recombinant protein corresponding to human CBX3 expressed in E. coli
DMAb-1118-YY	CBYY-C1039	Mouse	Human	IgG1	Recombinant fragment of human CBX3 expressed in E. Coli
DMAb-0730-FY	CBFYH-0050	Mouse	Human	IgG	29-86 of 183 of CBX3 Protein
DMAb-0778-FY	CBFYH-2920	Mouse	Human	IgG1	Recombinant HP1-gamma mouse
DMAb-0779-FY	CBFYH-2921	Mouse	Human	IgG1
DMAb-0780-FY	CBFYH-2922	Rat	Human	IgM	Full length recombinant protein
DMAb-0781-FY	CBFYH-0043	Mouse	Human	IgG1	Recognizes mouse Heterochromatin protein-1 gamma at ~22kD. Species Crossreactivity: human, rat.
DMAb-0782-FY	CBFYH-0044	Mouse	Human	IgG1	Recombinant mouse HP1gamma
DMAb-0783-FY	CBFYH-0045	Mouse	Human	IgG1	Fusion protein corresponding to aa17-173 of human Heterochromatin Protein 1 gamma with GST
DMAb-0784-FY	CBFYH-0046	Mouse	Human	IgG
DMAb-0785-FY	CBFYH-0047	Mouse	Human		Recombinant protein
DMAb-0786-FY	CBFYH-0048	Mouse	Human
DMAb-0787-FY	CBFYH-0049	Mouse	Human	IgG1	114-173 of 183 of CBX3 Protein
DMAb-0788-FY	CBFYH-0051	Mouse	Human
DMAb-0789-FY	CBFYH-0052	Rabbit	Human	IgG
DMAb-0790-FY	CBFYH-0053	Rabbit	Human	IgG
DMAb-0791-FY	CBFYH-0054	Mouse	Human	IgG1	Purified recombinant human HP1-gamma protein fragments expressed in E.coli
DMAb-0792-FY	CBFYH-0055	Mouse	Human	IgG2a
DMAb-2680-FY	CBFYC-0898	Mouse	Human	IgG2a
DMAb-2681-FY	CBFYC-0899	Mouse	Human	IgG2a, k
DMAb-2682-FY	CBFYC-0900	Mouse	Human	IgG2a, k	Full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
DMAb-1749-FY	CBFYM-0898	Rat	Human	IgM	This item recognises the M32 molecule in mouse and the HP1 HS gamma molecule in man
DMAb-0135-CQ	CBXC-0101	Mouse		IgG1
DMAb-0136-CQ	CBXC-0099	Mouse		IgG2a, κ
DMAb-0137-CQ	CBXC-0100	Mouse		IgG2a, κ
DMAb-0138-CQ	CBXC-2953	Mouse		IgG1	Purified recombinant human HP1-gamma protein fragments expressed in E. coli

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CBX3 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1117-YY)

Specifications

Target

Customer Reviews and Q&As

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