Anti-CDH1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2784-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-CDH1 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
CDH1

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
999

UniProt ID
P12830

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0014-FY	24E10	Rabbit		IgG
DMAb-0015-FY	67A4	Mouse		IgG1
DMAb-0016-FY	967717	Mouse	Human	IgG2a	Human embryonic kidney cell line HEK293-derived transfected with human E-Cadherin
DMAb-0017-FY	AR38.2	Mouse		IgG1	Recombinant Fizzy Related Protein
DMAb-0018-FY	CDH1/1121	Mouse	Human	IgG1, κ	Recombinant fragment of human E-Cadherin protein
DMAb-0019-FY	CDH1/1525	Mouse	Human	IgG1, κ	Recombinant human full-length E-Cadherin protein
DMAb-0020-FY	CL1172	Mouse	Human	IgG1	This antibody was developed against a recombinant protein corresponding to amino acids: ATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGA
DMAb-0021-FY	DECMA-1	Rat		IgG1
DMAb-0022-FY	ECCD-1	Rat	Mouse	IgG2b	Mouse teratocarcinoma cell line F9
DMAb-0023-FY	ECCD-2	Rat	Mouse	IgG2a	Mouse liver E-cadherin fragment
DMAb-0024-FY	EP700Y	Rabbit	Human	IgG
DMAb-0025-FY	HECD-1	Mouse	Human	IgG1	Human breast tumor cell line MCF-7
DMAb-0026-FY	NCH-38	Mouse		IgG1, κ	E-cadherin and GST recombinant protein
DMAb-0027-FY	SHE78-7	Mouse	Human	IgG2a	Soluble E-cadherin from human placenta
DMAb-0028-FY	SPM381	Mouse	Human	IgG1, κ	Recombinant human full-length E-Cadherin protein
DMAb-0360-CQ	CDH1/1122	Mouse	Human	IgG1, κ
DMAb-0361-CQ	DH01	Mouse	Human	IgG1, κ
DMAb-0367-CQ	813CT11.1.3	Mouse	Human	IgG1	Purified His-tagged CDH1 protein
DMAb-0369-CQ	MB2	Mouse	Human	IgG2b
DMAb-097-YC	GT477	Mouse	Human	IgG2a	Recombinant protein encompassing a sequence within the center region of human E-Cadherin.
DMAb-098-YC	GT311	Mouse	Human	IgG1	Recombinant protein encompassing a sequence within the center region of human E-Cadherin.
DMAb-099-YC	GT358	Mouse	Human	IgG2b	Recombinant protein encompassing a sequence within the center region of human E-Cadherin.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-CDH1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2784-FY)

Specifications

Target

Customer Reviews and Q&As

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