Anti-MAPK6 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1992-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-MAPK6 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
MAPK6

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
5597

UniProt ID
Q16659

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1992-FY	CBFYM-1629	Mouse	Human	IgG	Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, E. coli-derived recombinant human ERK3 (rhERK3, AA 344-721
DMAb-1993-FY	CBFYM-1630	Mouse	Human	IgG1	Recombinant fragment of human ERK3 expressed in E. coli
DMAb-1994-FY	CBFYM-1631	Mouse	Human	IgG2a	MAPK6 antibody was raised in mouse using a recombinant protein expressed in E. coli corresponding to amino acids 345-721 of human ERK3
DMAb-1995-FY	CBFYM-1632	Mouse	Human	IgG2b, k	Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
DMAb-1996-FY	CBFYM-1633	Mouse	Human	IgG2a, k
DMAb-1997-FY	CBFYM-1634	Rabbit	Human	IgG
DMAb-0595-FY	CBFYE-1538	Mouse	Human	IgG1	The immunogen corresponding to human ERK3 expressed in E.coli
DMAb-0596-FY	CBFYE-1539	Mouse	Human	IgG2a	Recombinant protein expressed in E.coli corresponding to amino acids 345-721 of human ERK3
DMAb-0597-FY	CBFYE-1540	Mouse	Human	IgG2a	Recombinant protein expressed in E.coli corresponding to amino acids 345-721 of human ERK3
DMAb-0598-FY	CBFYE-1541	Rabbit	Human	IgG	Synthetic peptide corresponding to human ERK3 at N-terminal

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-MAPK6 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1992-FY)

Specifications

Target

Customer Reviews and Q&As

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