Using simple, well-established platforms, researchers can explore significant unmet needs in life science research using biomarker analysis technology. Nowadays, Creative Biolabs offers the option of developing single or multiplex homebrew assays to minimize the sample volume, providing one-stop biomarker analysis that include all reagents and training required to develop these custom assays.
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP11, also known as A-kinase anchor protein 11, is involved in the control of somatic and germ cell cycles by targeting and binding to protein kinase A. Scientists proposed that AKAP11-mediated cAMP/PKA activation via selective autophagy should be explored in the future as a therapeutic target for cancer treatment. Studies have also provided evidence the rs9533090 polymorphism in AKAP11 influences calcaneal quantitative ultrasound (QUS) parameters during youth.
Ready to take your biomarker research to the next level?
Robust biomarker analysis is important for the accurate diagnosis of diseases and is of great value in cancer management. To complement our range of immunoassays, Creative Biolabs offers LC-MS/MS technology that has enabled us to extend our portfolio to include more biomarkers such as steroidal and hormonal substances in the low picogram range. We have also invested in the field of multiplexing, using bead-based suspension and electro-chemiluminescence-based platforms to offer robust immunoassays for application in clinical trials.
Fig.1 Comprehensive biomarker analysis services at Creative Biolabs.
As an experienced antibody developer, Creative Biolabs provides custom conjugation services for our anti- AKAP11 antibody to supply your specific research demands. Currently, there is a growing interest in identifying genetic markers associated with disease phenotypes to develop genetic screening strategies. Sequence variants and/or copy number variants within the AKAP11 gene could also be detected with high sensitivity. Our popular services include but are not limited to the following:
| Cat | Service |
| BAS78-1 | AKAP11 Polymorphism Analysis |
| BAS78-2 | AKAP11 Knockout Cell Line Generation |
| BAS78-3 | AKAP11-PKA Interaction Analysis |
| BAS78-4 | AKAP11 Protein Expression Analysis |
| BAS78-5 | AKAP11 mRNA Expression Analysis |
If you are interested in our services, please don't hesitate to contact us today to develop a custom solution for specific needs. We will work to accommodate your request.
For Research Use Only.
