Biomarkers are observable flags in samples that indicate specific states in a biological process such as disease progression. The importance of protein biomarkers lies in the fact that proteins are much easier to measure than the complex events they represent, and they are valuable at so many stages of the drug development process. Nowadays, Creative Biolabs provides solution to help you find the best analytical platform not only for your ALPK2 project in early or late stage of drug discovery but also in the preclinical phase.
Background
Alpha-kinase 2 (ALPK2), a member of alpha protein kinase family, contains a 2,170-amino acid isoform that is 237 kDa. ALPK2 was known to play a vital role in cancer by regulating cell cycle and DNA repair. It was identified as a key regulator in cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling.
Diagnostic Powder
Biomarker research to the next level?
At present, research on the mechanism of ALPK2 in cancer is still scarce. With the development of powerful technologies for proteomics, PTM analysis, protein quantitation, Creative Biolabs offers custom biomarker analysis for global clients. To understand the functions of ALPK2 and their place in complex biological systems, it is often important to measure changes in protein abundance relative to changes in the state of the system. These measurements have traditionally been performed using WB, IHC, ICC, IF, and ELISA.
Currently, modern proteomics has evolved to include various technologies for the routine quantitative analyses of both known and unknown targets. Creative Biolabs validates all antibodies on WB, IHC, ICC, IF, and ELISA with known positive and negative samples to ensure specificity and high affinity. Recombinant ALPK2 proteins are available to be used as a blocking antigen for antibody competition assays or tailored assays. The followed assays have been successfully proven to determine biomarkers in the specific biological samples.
| Cat | Service |
|---|---|
| BAS98-1 | Construction of ALPK2 Knockdown Cell Model |
| BAS98-2 | ALPK2 Protein Expression Analysis |
| BAS98-3 | ALPK2-Protein Interaction Analysis |
| BAS98-4 | ALPK2 Gene Mutation Analysis |
Creative Biolabs offers one-stop services for biomarker analysis using our advanced protein expression platform technologies. We hold extensive expertise in a wide range of biomarker assay development and validation services to meet your needs. If you are interested in our services, please don't hesitate to contact us today to develop custom solution for specific needs. We will work to accommodate your request.
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