Creative Biolabs guarantees highest discovery power for maximum outcome. Data derived from our biomarker services provides valuable tools to determine the biomarker expression level or how the drug exerts its effects in terms of efficacy and safety. Creative Biolabs offers amphiphysin (AMPH) biomarker analysis services through a network of experts familiar with the multifaceted nature of biomarker validation, and application from drug discovery to sample analysis supporting decision making and mitigating risk at key stages of your program.
Background
AMPH, a 125 kDa synaptic vesicle-associated protein, regulates the release of vesicle contents from excitable cells. AMPH is expressed in neuroendocrine cells, neurons, and spermatocytes. Amphiphysin can be phosphorylated at multiple sites in response to cell stimulation. It is also involved in actin polymerization during phagocytosis, spermatid release from Sertoli cells, and neurite outgrowth.
AMPH antibodies are associated with breast cancer, small-cell lung cancers, and neurological disorders. The presence of anti-AMPH autoantibodies is most associated with limbic encephalitis (LE) and stiff-person syndrome.
Increase Your Chance for Paramount Discoveries
All AMPH reagents are produced in house and quality controlled. With in-depth understanding of AMPH-IgG and its associated diseases, Creative Biolabs provides reliable biomarker AMPH analysis services from multiple dimensions. Using native AMPH samples or self-developed recombinant proteins, Creative Biolabs defines AMPH-IgG by immunohistochemical characteristics, and always confirmed autoantibody specificities by immunoblotting, the gold standard for the identification of intracellular antibodies. Collectively, featured AMPH services at Creative Biolabs include but not limited to the following:
| Cat | Service |
|---|---|
| BAS103-1 | AMPH-IgG Detection |
| BAS103-2 | AMPH Interaction Analysis |
| BAS103-3 | Knockdown of AMPH |
| BAS103-4 | AMPH PTMs Detection |
| BAS103-5 | Anti- AMPH Antibody Development |
You want to identify new biomarkers? Creative Biolabs accelerates your research from hypothesis to candidate validation!
For Research Use Only.
