Creative Biolabs provides a variety of readout options for biomarker ankyrin-B (ANK2) analysis to gain an additional layer of information and allow assay setups tailored to our customer's specific research needs.
Background
ANK2 gene encodes a member of the ankyrin family of proteins which link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. It has been pointed out as a candidate gene for the etiology of Autism spectrum disorders (ASD). Besides, downregulated ANK2 mRNA expression has been found in colorectal and thyroid cancer. Reported findings suggest that ANK2 gene mutation or increased ANK2 expression may serve as a favorable biomarker for the efficacy of immune checkpoint inhibitors in patients with advanced lung adenocarcinoma (LUAD).
Fig.1 Diagrammatic overview of ANK2 isoforms.1
Increase Your Chance for Paramount Discoveries
Professional biomarker analysis is crucial for the disease in vitro research. Comprehensive and accurate detection of the biomarker candidate is of pivotal importance in the drug discovery process. Creative Biolabs provides biomarker detection & analysis services by utilizing immunoassays, molecular assays, or one-stop integrated solution. Our featured cell-based assays are an excellent choice for screening after initial hit discovery due to the inherent nature of testing compound action in intact, living cells. Collectively, featured ANK2 services at Creative Biolabs include but not limited to the following:
| Cat | Service |
|---|---|
| BAS104-1 | ANK2 Mutation Analysis |
| BAS104-2 | ANK2 Expression Analysis |
| BAS104-3 | ANK2 Variant Identification |
| BAS104-4 | ANK2 Antibody Development |
| BAS104-5 | Custom Tailored ANK2 Assay Services |
Why Choose Creative Biolabs for Biomarker Research?
Creative Biolabs will help you develop an optimal treatment for ANK2 analysis. we've accumulated the largest portfolio of biomarker assays available. You can trust our expertise in providing tailored assay development. Work with us and you're guaranteed to get the exact in vitro biomarker assay you need. Creative Biolabs accelerates your research from hypothesis to candidate validation!
If you are interested in our ANK2 analysis services, please feel free to contact us for more information.
Reference
- York, Nicole S., et al. "Mechanisms underlying the role of ankyrin-B in cardiac and neurological health and disease." Frontiers in Cardiovascular Medicine 9 (2022): 964675. Distributed under CC BY-SA 4.0, without modification.
For Research Use Only.
