Human OPN Protein (Ile 17-Asn 300) [His] (VAng-2624Lsx)
Human Osteopontin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH07016)
Datasheet
Specifications
Source
HEK293 cells
Target
SPP1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 80% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
SPP1 (Secreted Phosphoprotein 1) is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Diseases associated with SPP1 include Bone Giant Cell Tumor and Calcific Tendinitis.
Alternative Names
SPP1, BNSP, OPN, Uropontin, Nephropontin, Osteopontin, BSP-1, ETA-1, BSPI
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