Anti-BAX DNA-encoded mAb (DMAb), pVAX1 (DMAb-0034-YY)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-BAX DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • BAX
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
  • Background
  • DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

  • Entrez Gene ID
  • 581
Sub CAT. DMAb Clone DMAb Host Target Species DMAb Isotype DMAb Immunogen  
DMAb-0034-YY CBYY-0213 Mouse Human IgG1 BAX monoclonal antibody was raised against a synthetic peptide of BAX (Human)
DMAb-0035-YY CBYY-0214 Mouse Human IgG1 Synthetic peptide corresponding to aa15 from human Bax
DMAb-0036-YY CBYY-0216 Mouse Human IgG
DMAb-0037-YY CBYY-0217 Rat Mouse IgG2b, κ Full length recombinant corresponding to aa1-192 from human BAX (AAH14175) with GST tag. MW of the GST tag alone is 26kD
DMAb-0038-YY CBYY-0218 Rabbit Human IgM A mixture of three synthetic peptides corresponding to the N-terminal, internal and C-terminal regions of human Bax inhibitor 1. [UniProt# P55061]
DMAb-0039-YY CBYY-0219 Rabbit Human IgG2a
DMAb-0040-YY CBYY-0220 Rabbit Human IgA Synthetic peptide
DMAb-0041-YY CBYY-0221 Rabbit Human IgG2b Recombinant human Bax
DMAb-0042-YY CBYY-0222 Rabbit Human IgG
DMAb-0043-YY CBYY-0223 Rabbit Human IgG2b, κ A partial length recombinant protein of human Bi-1 (amino acids 1-200)
DMAb-0044-YY CBYY-0226 Rabbit Human IgG1
DMAb-0045-YY CBYY-0227 Rabbit Human IgG1, κ
DMAb-0046-YY CBYY-0228 Rabbit Human IgG1 Human Bax, aa 3-16
DMAb-0047-YY CBYY-0229 Rabbit Human IgG1 Human Bax, aa 12-24
DMAb-0476-YY CBYY-1900 Rat Mouse IgG1, κ
DMAb-0505-YY CBYY-1986 Mouse Human IgG1
DMAb-0493-YY CBYY-1958 Mouse Human IgG2b, κ A mixture of three synthetic peptides corresponding to the N-terminal, internal and C-terminal regions of human B1. Epitope mapping indicates that the antibody recognizes an epitope in the N-terminal region of Bi-1
DMAb-0494-YY CBYY-1959 Mouse Human IgG2b, κ A mixture of three synthetic peptides corresponding to the N-terminal, internal and C-terminal regions of human Bi-1. Epitope mapping indicates that the antibody recognizes an epitope in the N-terminal region of Bi-1
DMAb-0417-YY CBYY-1713 Rabbit Human IgG2a S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Bax minus the carboxyl terminal
DMAb-0448-YY CBYY-1816 Mouse Human IgM Synthetic peptide corresponding to the N-terminal, internal and C-terminal regions of human Bi-1
DMAb-0513-YY CBYY-2012 Mouse IgG1 Human Bax-α aa. 55-178
DMAb-0546-YY CBYY-2115 Rabbit Human IgG2b BAX Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human BAX
DMAb-0549-YY CBYY-2122 Mouse Human IgG1, κ Aa8-16 from mouse Bax

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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