Anti-BST2 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0407-YY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-BST2 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
BST2

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
684

UniProt ID
Q10589

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0407-YY	CBYY-1678	Rabbit	Human	IgG1, κ	Full length recombinant human BST2 protein [NCBI NP_004326]
DMAb-0208-YY	CBYY-0848	Rat	Human	IgG2a, κ	Full length recombinant corresponding to aa40-180 from human BST2 (AAH33873) with GST tag. MW of the GST tag alone is 26kD
DMAb-0434-YY	CBYY-1770	Mouse	Human		BST2 (AAH33873.1, 1aa-180aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD
DMAb-0461-YY	CBYY-1859	Mouse	Human	IgG1, κ	mouse plasmatocytoid DCs (pDCs)
DMAb-0542-YY	CBYY-2102	Mouse	Human	IgG1, κ	Full length recombinant human BST2 protein [NCBI NP_004326]
DMAb-0530-YY	CBYY-2069	Mouse	Human	IgG2a	Recombinant extracellular domain of CD317
DMAb-0054-CQ	CBXC-0740	Human		IgG1
DMAb-1746-FY	CBFYM-0007	Rat	Mouse	IgG2b
DMAb-2618-FY	CBFYC-0490	Mouse	Human	IgG1, k
DMAb-2619-FY	CBFYC-0585	Rat	Mouse	IgG2b, k	Mouse plasmacytoid dendritic cells (DCs)
DMAb-0033-WJ	CBWJC-0020	Rat	Mouse	IgG2b, κ
DMAb-0034-WJ	CBWJC-0021	Rat	Mouse	IgG2b, κ
DMAb-0035-WJ	CBWJC-0392	Rat	Mouse	IgG1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-BST2 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0407-YY)

Specifications

Target

Customer Reviews and Q&As

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