Anti-GSK3B DNA-encoded mAb (DMAb), pVAX1 (DMAb-1510-LY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-GSK3B DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
GSK3B

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
2932

UniProt ID
P49841

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1510-LY	10K22	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1511-LY	11B9	Mouse		IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1512-LY	1253C	Rabbit	Human	IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1387-LY	1F7	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1514-LY	1V001	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1515-LY	272535	Rat	Human	IgG2b	Glycogen Synthase Kinase 3 Beta
DMAb-1516-LY	272536	Rat		IgG2b	Glycogen Synthase Kinase 3 Beta
DMAb-449-YC	3A11	Mouse		IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-1518-LY	3A6	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-3823CQ	3D10	Mouse		IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-1520-LY	3D6B4	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1521-LY	5D6	Mouse	Human	IgG2b	Glycogen Synthase Kinase 3 Beta
DMAb-1522-LY	5K150	Mouse	Human	IgG2b	Glycogen Synthase Kinase 3 Beta
DMAb-1523-LY	5K151	Mouse	Human	IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-1524-LY	609739	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1525-LY	6D424	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1527-LY	8H133	Rat		IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-1437-LY	SBGSK3a4	Mouse		IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-1529-LY	Y174	Rabbit	Human	IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1536-LY	10F602	Mouse		IgG2	Glycogen Synthase Kinase 3 Beta
DMAb-1537-LY	11n79	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1538-LY	13G34D5C5Z	Rabbit		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1539-LY	1A6	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1111-LY	1H3	Mouse	Human	IgG2a, κ	Glycogen Synthase Kinase 3 Beta
DMAb-1541-LY	1H9L3	Rabbit	Human	IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1542-LY	2C6	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1543-LY	2E6-D6-C12	Mouse		IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-M106-YC	4D2	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1545-LY	6C2	Mouse		IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1546-LY	8H132	Rat	Human	IgG2b	Glycogen Synthase Kinase 3 Beta
DMAb-1547-LY	AF12E8	Mouse		IgG1, κ	Glycogen Synthase Kinase 3 Beta
DMAb-1548-LY	D5C5Z	Rabbit		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-1549-LY	E.948.2	Rabbit		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-169-YC	G8	Mouse		IgG2a	Glycogen Synthase Kinase 3 Beta
DMAb-1554-LY	M131	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1555-LY	M132	Mouse		IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1556-LY	MM0748-19G29	Rat	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1557-LY	P1F7AT	Mouse		IgG1, κ	Glycogen Synthase Kinase 3 Beta
DMAb-1558-LY	TS106	Mouse	Human	IgG1	Glycogen Synthase Kinase 3 Beta
DMAb-1559-LY	ZG004	Mouse		IgG	Glycogen Synthase Kinase 3 Beta
DMAb-3823CQ	3D10	Mouse		IgG2a	Purified recombinant C-terminal fragment of Human GSK3 beta expressed in E. coli.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-GSK3B DNA-encoded mAb (DMAb), pVAX1 (DMAb-1510-LY)

Specifications

Target

Customer Reviews and Q&As

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