Anti-MYH14 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2543-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-MYH14 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
MYH14

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
79784

UniProt ID
Q7Z406

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-2543-FY	CBFYM-0068	Mouse	Human	IgG1, k	Full length native protein (purified) (Human)
DMAb-2544-FY	CBFYM-0361	Mouse	Human	IgG2b	Chicken pectoralis-derived Myosin
DMAb-2545-FY	CBFYM-0768	Mouse	Human	IgG1
DMAb-2546-FY	CBFYM-2921	Mouse	Human		Chicken muscle cells
DMAb-2547-FY	CBFYM-2922	Human	Human		Fusion protein of a domain of murine mFLJ00279 (amino acid residues 958-1201, MW 28 kDa) expressed in E. coli
DMAb-2548-FY	CBFYM-2923	Mouse	Human	IgG	Recognizes human myosin heavy chain
DMAb-2549-FY	CBFYM-2924	Mouse	Human	IgG	KLH conjugated synthetic peptide encompassing a sequence within the N-term region of human myosin heavy chain
DMAb-2550-FY	CBFYM-2925	Mouse	Human	IgG	Purified human cardiac myosin heavy chain
DMAb-2551-FY	CBFYM-2926	Mouse	Human	IgM	Smooth muscle myosin
DMAb-2552-FY	CBFYM-2927	Mouse	Human	IgG1	Myosin isolated from rabbit skeletal muscle
DMAb-2553-FY	CBFYM-2928	Rabbit	Human	IgG
DMAb-2554-FY	CBFYM-2929	Mouse	Human	IgG1	Rabbit muscle myosin
DMAb-2555-FY	CBFYM-2930	Mouse	Human	IgG1	Native myosin heavy chain from muscle

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-MYH14 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2543-FY)

Specifications

Target

Customer Reviews and Q&As

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