Anti-NPM1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1583-WJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-NPM1 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

Add to Cart

Specifications

Target
NPM1

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
4869

UniProt ID
P06748

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0781-YJ	5E3	Mouse	Human	IgG2b	Recombinant human NPM (81-294aa) purified from E. coli
DMAb-1584-WJ	23F1	Mouse	Human	IgG1, κ	Recombinant human NPM1(1-294aa) purified from E. coli
DMAb-1585-WJ	3A9F1	Mouse	Human	IgG1
DMAb-1587-WJ	NA24	Mouse	Human	IgG, κ
DMAb-1588-WJ	1042CT5-2-1	Mouse	Human	IgG1	Purified His-tagged NPM1 protein was used to produced this monoclonal antibody
DMAb-0247-LY	1B11	Mouse	Human	IgG1, κ	NPM1 (AAH02398.1, 1 a.a. ~ 294 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
DMAb-420-YC	3B2	Mouse	Human	IgG1, κ	NPM1 (AAH02398.1, 1 a.a. ~ 294 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
DMAb-1594-WJ	3C9	Mouse	Human	IgM	Total extracts of Daudi cell nuclei
DMAb-1596-WJ	7H10B9	Mouse		IgG1
DMAb-1597-WJ	AT23F1	Mouse	Human	IgG1, κ
DMAb-1598-WJ	D19C1	Rabbit		IgG
DMAb-1603-WJ	FC82291	Mouse		IgG1	rat B23 (nucleophosmin, NPM, numatrin)
DMAb-1604-WJ	No-185	Mouse		IgG1	Nucleolar fraction prepared from Xenopus laevis oocytes
DMAb-1605-WJ	No-63	Mouse		IgG2a	Nucleolar fraction prepared from Xenopus laevis oocytes
DMAb-1606-WJ	P87H10B9	Mouse	Human	IgG1, κ	Purified recombinant human nucleophosmin (2-265 a.a.) expressed in E. coli

Customer Reviews and Q&As

There are currently no customer reviews or questions for Anti-NPM1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1583-WJ). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-NPM1 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1583-WJ)

Specifications

Target

Customer Reviews and Q&As

Related Products

CAR Vector Products