Anti-SEMA6A DNA-encoded mAb (DMAb), pVAX1 (DMAb-2168-CQ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-SEMA6A DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
SEMA6A

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
57556

UniProt ID
Q9H2E6

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-2168-CQ	CBXS-3646	Mouse		IgG1	Sema-6A
DMAb-2169-CQ	CBXS-3597	Mouse		IgG1	Sema-6A
DMAb-2170-CQ	CBXS-5756	Rat		IgG2	Mouse recombinant protein of Semaphorin 6A extracellular domain
DMAb-2171-CQ	CBXS-5931	Mouse		IgG2	Human recombinant Semaphorin 6A EC domain
DMAb-2172-CQ	CBXS-0208	Mouse		IgG2b
DMAb-2173-CQ	CBXS-1045	Rabbit		IgG	Recombinant Human Semaphorin 6A/SEMA6A protein
DMAb-2174-CQ	CBXS-1155	Rabbit		IgG
DMAb-2175-CQ	CBXS-1680	Mouse		IgG2b	NS0-derived recombinant human Semaphorin 6A, Gly19-Thr649, Accession # Q9H2E6
DMAb-2176-CQ	CBXS-1694	Rat		IgG2a	Sf 21-derived recombinant mouse Semaphorin 6A, Gly19-Thr649, Accession # O35464
DMAb-2177-CQ	CBXS-2553	Mouse		IgG2	Recombinant protein corresponding to human Semaphorin 6A EC domain
DMAb-2178-CQ	CBXS-2554	Rat		IgG2	Recombinant protein corresponding to mouse Semaphorin 6A
DMAb-2179-CQ	CBXS-2725	Mouse		IgG2a, κ	Partial recombinant corresponding to aa21-121 from human SEMA6A (NP_065847) with GST tag
DMAb-2180-CQ	CBXS-3511	Mouse		IgG2b	NS0-derived, recombinant human Semaphorin 6A aa19-649; Q9H2E6 extracellular domain

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-SEMA6A DNA-encoded mAb (DMAb), pVAX1 (DMAb-2168-CQ)

Specifications

Target

Customer Reviews and Q&As

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