Anti-SOX9 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2793-CQ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-SOX9 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
SOX9

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
6662

UniProt ID
P48436

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-2793-CQ	CBXS-5445	Rabbit		IgG
DMAb-2794-CQ	CBXS-5607	Mouse		IgG1, κ	SOX9 (NP_000337, 400aa-509aa) partial recombinant protein with GST tag
DMAb-2795-CQ	CBXS-3856	Mouse		IgG1	Purified recombinant fragment of human SOX9
DMAb-2796-CQ	CBXS-4642	Mouse		IgG1	Human recombinant protein fragment corresponding to amino acids 1-205 of human SOX9 (NP_000337)
DMAb-2797-CQ	CBXS-4697	Mouse		IgM	KLH conjugated synthetic peptide between 41-70 amino acids from human SOX9
DMAb-2798-CQ	CBXS-4790	Mouse		IgG2a, κ
DMAb-2799-CQ	CBXS-4911	Mouse		IgG1
DMAb-2800-CQ	CBXS-5319	Mouse		IgG2a	Recombinant protein corresponding to amino acids: SQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTR
DMAb-2801-CQ	CBXS-0671	Mouse
DMAb-2802-CQ	CBXS-1332	Rabbit		IgG
DMAb-2803-CQ	CBXS-1333	Rabbit		IgG
DMAb-2804-CQ	CBXS-1376	Rabbit		IgG
DMAb-2805-CQ	CBXS-1377	Rabbit		IgG
DMAb-2806-CQ	CBXS-2202	Mouse
DMAb-2807-CQ	CBXS-2462	Mouse		IgG1	Purified recombinant fragment of human SOX9
DMAb-2808-CQ	CBXS-2821	Mouse			SOX9 (NP_000337, 400aa-509aa) partial recombinant protein with GST tag
DMAb-2809-CQ	CBXS-6157	Mouse		IgG1, κ

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-SOX9 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2793-CQ)

Specifications

Target

Customer Reviews and Q&As

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