Anti-SPINT2 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1618-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-SPINT2 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
SPINT2

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
20733

UniProt ID
Q9WU03

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-1618-FY	CBFYH-3308	Rat	Mouse	IgG2	Mouse recombinant protein of the common extracellular region of HAI-2 isoforms
DMAb-1619-FY	CBFYH-2780	Mouse	Human	IgG1	Mouse myeloma cell line NS0-derived recombinant human HAI-2, aa 28-197
DMAb-1620-FY	CBFYH-2781	Mouse	Human	IgG1	Human recombinant HAI-2 EC domain
DMAb-1621-FY	CBFYH-2782	Rabbit	Human	IgG
DMAb-3241-FY	CBFYC-0045	Mouse	Human	IgG1	Recombinant Human CD200 Protein
DMAb-3242-FY	CBFYC-0098	Rabbit	Mouse	IgG	Recombinant Mouse CD200 protein (50074-M08H)
DMAb-3243-FY	CBFYC-3137	Rabbit	Mouse	IgG	Recombinant Mouse CD200 protein
DMAb-2875-CQ	CBXS-5889	Rat		IgG2
DMAb-2876-CQ	CBXS-3763	Mouse		IgG1
DMAb-2877-CQ	CBXS-1161	Rabbit		IgG	Recombinant Mouse SPINT2 protein
DMAb-2878-CQ	CBXS-2593	Mouse		IgG1	Recombinant protein corresponding to human SPINT2 extracellular domain
DMAb-2879-CQ	CBXS-2867	Mouse		IgG2a, κ	Full length recombinant protein corresponding to aa1-253 from SPINT2 (AAH11951) with GST tag
DMAb-M331-YC	RM0089-7F52	Rat	Mouse	IgG2	Recombinant fragment corresponding to the extracellular region of Mouse HGFA Inhibitor 2.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-SPINT2 DNA-encoded mAb (DMAb), pVAX1 (DMAb-1618-FY)

Specifications

Target

Customer Reviews and Q&As

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