Anti-TAG 72 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0530-YJ)

Name: Anti-TAG 72 DNA-encoded mAb (DMAb), pVAX1
SKU: DMAb-0530-YJ
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-TAG 72 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
TAG 72

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0530-YJ	CA72/145	Mouse	Human	IgG1, κ	Human CA72.4 protein
DMAb-0531-YJ	CA72/733	Mouse		IgG1, κ	Recombinant human TAG-72 protein
DMAb-0532-YJ	CC49	Mouse		IgG1, κ	Purified TAG-72 protein
DMAb-0533-YJ	SPM536	Mouse		IgG1, κ	Purified TAG-72 protein
DMAb-0534-YJ	B72.3	Mouse		IgG1, κ	A membrane enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for the TAG-72 (B72.3) antibody
DMAb-0535-YJ	SPM148	Mouse		IgG1, κ	Membrane-enriched fraction of a human breast carcinoma liver metastasis

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-TAG 72 DNA-encoded mAb (DMAb), pVAX1 (DMAb-0530-YJ)

Specifications

Customer Reviews and Q&As

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