CAR Modified T Cells

Creative Biolabs offers CellRapeutics™ Chimeric Antigen Receptor (CAR) production service with the highest quality. As a leading service provider, our experienced scientists are glad to provide highly customized, reliable and effective solutions for our customers.

T cells play a critical role in cell-mediated immunity, which can attack and kill cancer cells. However, cancer cells can usually avoid being attacked by T cells via a series of defense mechanisms. Recently, genetically modified T cell immunotherapy which targets tumor via directly recognizing tumor associated antigen, has become one of the most attractive approaches for treating various cancers.

A classic CAR molecule usually composes of a single chain antibody (scFv) domain, a transmembrane domain and cytoplasmic signaling domains. After the CAR-T cells being infused back into cancer patients, these modified T cells can directly recognize and kill the cancer cells which display tumor specific antigens. Experts from Creative Biolabs have successfully established cutting-edge CARs T cells construction platform, which can fit your application purpose according to the requirement.

Creative Biolabs has rich experience in developing CARs. Our skilled scientists and technicians guarantee that we can offer you unparalleled CARs-T cell construction services.

CAR Modified T cells

Fred Hutchinson Cancer Research Center website and Turtle CJ, Hudecek M, Jensen MC, Riddell SR. Engineered T cells for anti-cancer therapy. Curr Opin Immunol. 2012 Oct; 24(5):633-9.

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