• Process Development
• Analytical Development
• CAR-T Plasmid CDMO
  • RG CAR-T Plasmid DNA Manufacturing
  • GMP-like CAR-T Plasmid Manufacturing
  • GMP CAR-T Plasmid DNA Manufacturing
• CAR Viral Vector CDMO
  • RG CAR-T Virus Manufacturing
  • GMP-like CAR-T Virus Manufacturing
  • GMP CAR-T Virus Manufacturing
  • cGMP CAR-T AAV Production
  • cGMP CAR-T Lentivirus Production
  • cGMP CAR-T Retrovirus Production
  • Custom cGMP CAR-T Virus Production
• CAR IVT RNA & LNP Manufacturing
  • RG CAR-T mRNA Manufacturing
  • GMP-like CAR-T mRNA Manufacturing
  • GMP CAR-T mRNA Manufacturing
  • CAR-T Lipid Nanoparticle Encapsulation
• CAR Viral Vector Packaging
  • CAR-T AAV Packaging
  • CAR-T Lentivirus Packaging
• CAR Cell CDMO
  • IIT Grade CAR-T Manufacturing
  • IND Grade CAR-T Manufacturing
  • Clinical Grade CAR-T Manufacturing

CAR-T AAV Packaging Service

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Innovative genetic engineering and gene therapy approaches have transformed the landscape of medical research and clinical applications. A key component in these advanced therapies is the delivery system, where viral vectors play a crucial role. As a front-runner in this field, Creative Biolabs offers comprehensive CAR viral vector CDMO services, including both AAV packaging and lentivirus packaging, tailored to meet diverse research and therapeutic needs.

GMP AAV Packaging Service

At Creative Biolabs, our AAV packaging platform is designed to offer superior packaging services tailored specifically for CAR-T cell therapy. Leveraging years of expertise in gene therapy, we provide comprehensive solutions from vector design to production, ensuring the highest levels of efficacy and safety. We employ a scalable production process that accommodates various serotypes and payloads, allowing for versatility in addressing a wide range of therapeutic indications. Our AAV packaging utilizes robust methodologies to generate high-titer, high-purity AAV essential for CAR-T applications.

AAV Packaging Workflow

Our services encompass the entire process, including cell line development, optimization of transfection protocols, virus production, purification, and quality control, ensuring seamless and efficient delivery of AAV to meet your needs. Our packaging process is optimized for consistency and scalability, ensuring that we can meet both small and large-scale production needs.

Highlights

• Established Production System: Our well-established production system guarantees reliable and reproducible results, facilitating the seamless transition from research to clinical trials.
• Multiple Serotype Purification: We possess the expertise to purify multiple AAV serotypes, offering flexibility and specificity to meet diverse project requirements.
• High Efficiency: Our high-efficiency manufacturing processes are designed to maximize yield and minimize production time, ensuring timely delivery of high-quality AAV.
• Linear Scalability: Our cell culture systems are scalable from 25 to 2000L single-use bioreactors, providing flexibility to scale up production as needed without compromising quality or consistency.

Partner with Creative Biolabs

Our team of experts works closely with clients to develop tailored AAV packaging strategies that align with their specific project requirements. Whether you are conducting preclinical studies or embarking on clinical trials, Creative Biolabs' AAV packaging service is your reliable partner in achieving your goals.

Frequently Asked Questions

Q1: Which AAV serotypes can be used in your AAV packaging services?

Creative Biolabs offers packaging for a wide range of AAV serotypes, including but not limited to AAV1, AAV2, AAV5, AAV6, AAV8, and AAV9.

Q2: What tests are included in QC assays?

Our QC assays include tests for purity assessment using SDS-PAGE and HPLC, residual plasmid DNA analysis, residual host cell DNA and protein analysis, virus titer using qPCR and ELISA, sterility and endotoxin testing, among others. Each assay is designed to ensure the highest quality and compliance with regulatory standards.