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Cell Based Assays for Cancer Vaccine

Whether it is a protein, vaccine or other molecules, the efficacy of the therapeutic agent needs to be demonstrated before each batch is released, which is usually done in cell-based assays. Cell-based assays are an important tool for drug discovery because they provide physiological data on the effects of drugs.

Creative Biolabs has long-standing experience in cell-based assays, including primary cells, transformed cell lines, and transfected reporter cell systems. The expertise of scientists in Creative Biolabs can characterize many different biological activities of your molecule, such as cell growth, cell death, induction of immune effector function, biomarker expression, induction or inhibition of signaling events, and drug internalization. Our experts work closely with you to provide a fully validated efficacy test for your biologics for regulatory submissions and can be reused throughout the drug development process.

Our Cell Based Assays Services

Scientists in Creative Biolabs develop, validate and operate cell-based assays in a GLP regulatory environment to determine the safety and efficacy of biopharmaceuticals to support pre-clinical drug development. We use a range of cell-based analytical models to characterize recombinant proteins/monoclonal antibodies/vaccines (include but not limited to):

  • Customized potency assays
  • ADCC assays
  • ADCP assays
  • T-cell mediated cytotoxicity assay
  • Whole blood assays
  • CDC assays
  • Reporter-gene assays
  • Cell Proliferation
  • Cell Death (apoptosis / necrosis)
  • Cell Death (apoptosis / necrosis)
  • Receptor / Ligand Binding
  • Receptor Activation / Internalization
  • Cell migration & invasion
  • Cell adhesion (static and flow dynamic assays)
  • Biomarker Expression on protein (intracellular, secreted and surface marker analysis) and on mRNA level
  • Immune cell activation and proliferation
  • Cytokine quantification

Supported Products

  • Protein based therapeutics
  • Monoclonal antibodies
  • Cancer vaccines
  • Gene therapy products
  • Biosimilars
  • Etc.

For more details, please feel free to contact us for project quotations and more detailed information.

Online Inquiry

For any technical issues or products/services related questions, please leave your contacts as below, and our team will contact you at earliest convenience to let you know how we can be involved in your projects.

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