All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Ephrin type-B receptor 4 (EPHB4), a member of the family of receptor tyrosine kinases (RTKs), is ubiquitously expressed in distinct types of malignancies as rhabdomyosarcoma (RMS). In RMS and other malignancies, EPHRIN B2 interaction with EPHB4 may induce apoptosis and lack of proliferation (54). Based on the fact that EPHRIN B2 is a unique ephrin ligand that interacts with EPHB4, a second-generation CAR-T cell with an extracellular portion of EPHRIN B2 can be considered for RMS treatment.
Creative Biolabs provides a second-generation CAR vector which is designed using IL-11 peptide/protein as the extracellular domain. The vector is constructed for the engineering of T cells to target Human IL-13Rα.
There are currently no customer reviews or questions for EPHB4 (EPHRIN B2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 (XS-1222-ZP1406). Click the button below to contact us or submit your feedback about this product.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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