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Anti-Bet v I(aa 142-153) T cell receptor, pCDTCR1 (TCR-C012Z)

The vector of anti-Bet v I T cell receptor (TCR) is constructed for the engineering of T cell to target Birch Bet v I. The T cells are genetically modified through transduction with a lentiviral vector expressing Bet v I-specific T cell receptor. And the vector product was designed for the treatment of Allergic diseases.

Details

  • Target
  • Bet v1
  • Target Species
  • Birch
  • Epitope
  • aa 142-153
  • Format
  • Non-modified
  • HLA
  • HLA-DRB1*07:01
  • Targeting Diseases
  • Allergic diseases
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Host
  • Human

Target

  • Gene Name
  • Birch Pollen Allergen Bet V 1
  • Official Symbol
  • Bet v I
  • Synonyms
  • Bet v I; Birch Pollen Allergen Bet V 1
  • Introduction
  • Bet v I allergen is a family of protein allergens. Allergies are hypersensitivity reactions of the immune system to specific substances called allergens (such as pollen, stings, drugs, or food) that, in most people, result in no symptoms.
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