Primary Mouse CAR-T Cell Production Service

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Mouse models play a pivotal role in preclinical studies, allowing for the development and testing of CAR-T cell therapies. A primary source of mouse CAR-T cells serves as an essential resource for exploring the mechanisms that govern CAR-T response and performance post-adoptive transfer in both healthy and disease mouse models. With cutting-edge technologies and extensive expertise in the realm of CAR-T immunotherapy, Creative Biolabs stands ready to supply antigen-specific primary mouse CAR-T cells for evaluating their functionality within the mouse model.

General Workflow

The workflow of our primary mouse CAR-T cell production service is a meticulously designed process that encompasses the following key stages:

General Workflow

Features of Our Service

Various Mouse Primary T Cell Source

Mouse models used in CAR-T cell therapy testing include xenograft, humanized, syngeneic, and transgenic settings. We provide the proper model for you to isolate primary murine T cells, developing CAR-T products to test effectiveness and safety.
Primary mouse T cells derived from kinds of mouse strains (such as C57BL/6, Balb/C, NSG, and so on) are available.
Specific murine T cell subsets like CD4⁺T, CD8⁺T, or Treg can be sorted definitely for the production of CAR-T for murine-adoptive immunotherapy studies.

Retroviral And Non-viral Gene Transfer Methods Are Available

We have a robust CAR-T gene packaging and delivery system, including electroporation and retroviral transfection.
Our modified protocol can produce primary mouse CAR-T with high transduction efficiency and viability, and low cytotoxicity.

High Expansion Capability

We ensure large numbers of mouse CAR-T cells are generated with high viability and growth rate to satisfy your needs.
Our primary mouse CAR-T generated can survive more than two weeks in vivo and show persistent CAR expression that is fit for both in vitro and in vivo tests.

Verification of Primary Mouse CAR-T

Validation of CAR surface expression and in vitro cytotoxicity versus antigen-positive and antigen-negative target cells.
Other items including but not limited to cell purity, cell viability, mycoplasma testing, and sterility testing.

Creative Biolabs stands at the forefront of cell therapy, bolstered by a wealth of experience. We provide expert, cutting-edge services to clients worldwide, guiding them towards successful project completion. It is our commitment to advance your projects and expedite progress toward clinical trials through the utilization of our advanced technologies, platforms, and resources.

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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