ASIP

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008]
  • CAR Vector Products

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP301 ASIP (ATRN Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human ASIP-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP302 ASIP (MC1R Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human ASIP-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1701 ASIP (ATRN Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human ASIP-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1702 ASIP (MC1R Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human ASIP-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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