BMP8B

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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP1352 BMP8B (BMPR1A Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1353 BMP8B (BMPR1B Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1354 BMP8B (BMPR2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1355 BMP8B (ACVR1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1356 BMP8B (ACVR2A Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1357 BMP8B (ACVR2B Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2752 BMP8B (BMPR1A Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2753 BMP8B (BMPR1B Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2754 BMP8B (BMPR2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2755 BMP8B (ACVR1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2756 BMP8B (ACVR2A Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2757 BMP8B (ACVR2B Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human BMP8B-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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