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CEACAM1

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This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancyspecific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cellcell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue threedimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the fulllength nature of all variants has not been defined. [provided by RefSeq, May 2010]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-0120ZP2501 Anti-CEACAM1 (CM-24) h(CD28-CD3ζ) CAR, pCDCAR1 Humanized Human CM-24 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2502 Anti-CEACAM1 (CM-24) h(4-1BB-CD3ζ) CAR, pCDCAR1 Humanized Human CM-24 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2509 Anti-CEACAM1 (xp25) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human xp25 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2510 Anti-CEACAM1 (xp25) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human xp25 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2511 Anti-CEACAM1 (XP9) h(CD28-CD3ζ) CAR, pCDCAR1 Humanized Human XP9 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2512 Anti-CEACAM1 (XP9) h(4-1BB-CD3ζ) CAR, pCDCAR1 Humanized Human XP9 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2513 Anti-CEACAM1 (XP10) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human XP10 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2514 Anti-CEACAM1 (XP10) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human XP10 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2515 Anti-CEACAM1 (XP11) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human XP11 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2516 Anti-CEACAM1 (XP11) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human XP11 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2517 Anti-CEACAM1 (NEO-201) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human NEO-201 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2518 Anti-CEACAM1 (NEO-201) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human NEO-201 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2519 Anti-CEACAM1 (CC1) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human CC1 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2520 Anti-CEACAM1 (CC1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human CC1 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2521 Anti-CEACAM1 (xp26) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human xp26 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2522 Anti-CEACAM1 (xp26) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human xp26 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2523 Anti-CEACAM1 (CC1/3/5-Sab) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human CC1/3/5-Sab scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2524 Anti-CEACAM1 (CC1/3/5-Sab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human CC1/3/5-Sab scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2525 Anti-CEACAM1 (4D1/C2) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human 4D1/C2 scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2526 Anti-CEACAM1 (4D1/C2) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse Human 4D1/C2 scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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