F2

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Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP72 F2 (GP9 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP597 F2 (F2R Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP598 F2 (F2RL1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP599 F2 (F2RL2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP600 F2 (F2RL3 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1472 F2 (GP9 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1997 F2 (F2R Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1998 F2 (F2RL1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1999 F2 (F2RL2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2000 F2 (F2RL3 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human F2-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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