FGF8

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP651 FGF8 (FGFR1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP652 FGF8 (FGFR2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP653 FGF8 (FGFR3 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP654 FGF8 (FGFR4 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2051 FGF8 (FGFR1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2052 FGF8 (FGFR2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2053 FGF8 (FGFR3 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2054 FGF8 (FGFR4 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGF8-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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