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α-GalCer (C24)

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

alpha-Galactosylceramide (α-GalCer, KRN7000) is a synthetic glycolipid derived from structure-activity relationship studies of galactosylceramides isolated from the marine sponge Agelas mauritianus. α-GalCer is a strong immunostimulant and shows potent anti-tumour activity in many in vivo models. α-GalCer is a potent activator of iNKT cells, and a model CD1d antigen. The invariant T cell receptor of the iNKT cell is able to bind the CD1d:glycolipid complex leading to iNKT cell in both mice and humans.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC1429 Mouse anti-α-GalCer (C24) T cell receptor (Vβ8.2), pCDTCR1 Vβ8.2 Mouse α-galactosylceramide (C24) mouse CD1d Lentiviral vector   Add to Cart   Datasheet
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