GCG

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The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP681 GCG (GCGR Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human GCG-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP682 GCG (GLP1R Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human GCG-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP683 GCG (GLP2R Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human GCG-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2081 GCG (GCGR Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human GCG-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2082 GCG (GLP1R Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human GCG-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2083 GCG (GLP2R Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human GCG-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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