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GGCX

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This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LY1161 Anti-GGCX (CBLG1-090) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-090 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1162 Anti-GGCX (CBLG1-2747) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-2747 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1163 Anti-GGCX (CBLG1-1052) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-1052 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2801 Anti-GGCX(CBLG1-090) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-090 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2802 Anti-GGCX(CBLG1-2747) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-2747 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2803 Anti-GGCX(CBLG1-1052) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-1052 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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