GSKIP

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This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY0886 Anti-GSKIP (CBFYH-0509) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-0509 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4139 Anti-GSKIP (CBFYH-0509) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-0509 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1591 Anti-GSKIP (CBLG1-255) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-255 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1592 Anti-GSKIP (2F2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2F2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1593 Anti-GSKIP (CBLG1-1903) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-1903 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1594 Anti-GSKIP (CBLG1-1904) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-1904 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY3231 Anti-GSKIP(CBLG1-255) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-255 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY3232 Anti-GSKIP(2F2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2F2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY3233 Anti-GSKIP(CBLG1-1903) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-1903 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY3234 Anti-GSKIP(CBLG1-1904) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-1904 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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