HLA-E

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HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP730 HLA-E (KLRC1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human HLA-E-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP731 HLA-E (KLRC2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human HLA-E-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP732 HLA-E (KLRD1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human HLA-E-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2130 HLA-E (KLRC1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human HLA-E-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2131 HLA-E (KLRC2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human HLA-E-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2132 HLA-E (KLRD1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human HLA-E-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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