70 kD heat shock proteins(HSP70) are a family of conserved ubiquitously expressed heat shock proteins. Hsp70 proteins are central components of the cellular network of molecular chaperones and folding catalysts. They assist a wide range of folding processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and aggregated proteins, membrane translocation of organellar and secretory proteins, and control of the activity of regulatory proteins. Hsp70 is overexpressed in malignant melanoma and underexpressed in renal cell cancer.

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type  
CAR-LC255 Anti-HSP70 (cmHsp70.1) h(41BB-CD3ζ) CAR, pCDCAR1 Human cmHsp70.1 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Inquiry
CAR-LC256 Anti-HSP70 (Humanized cmHsp70.1) h(41BB-CD3ζ) CAR, pCDCAR1 Human Humanized cmHsp70.1 Human scFv-41BB-CD3ζ Lentiviral T cell   Inquiry

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