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IAV M1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place.
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CAT Product Name Cell Type Target HLA Epitope Inquiry & Datasheet
TCRJ-CQ132 Anti-IAV M1 (GILGFVFTL) T Cell Receptor (clone CB2A5), Jurkat Cell Line T lymphocyte IAV M1 HLA-A2 GILGFVFTL   Add to Cart   Datasheet
TCRJ-CQ229 Anti-IAV M1 (GILGFVFTL) T Cell Receptor (clone JM22), Jurkat Cell Line T lymphocyte IAV M1 HLA-A2 GILGFVFTL   Add to Cart   Datasheet
TCRJ-CQ230 Anti-IAV M1 (GILGFVFTL) T Cell Receptor (clone PF6), Jurkat Cell Line T lymphocyte IAV M1 HLA-A2 GILGFVFTL   Add to Cart   Datasheet
TCRJ-CQ231 Anti-IAV M1 (GILGFVFTL) T Cell Receptor (clone PF8), Jurkat Cell Line T lymphocyte IAV M1 HLA-A2 GILGFVFTL   Add to Cart   Datasheet
TCRJ-CQ232 Anti-IAV M1 (GILGFVFTL) T Cell Receptor (clone V(beta)17V(alpha)10.2), Jurkat Cell Line T lymphocyte IAV M1 HLA-A2 GILGFVFTL   Add to Cart   Datasheet
XS-0623-ZP165 Anti-IAV M1 TCR-NK Cells TCR-NK IAV M1   Add to Cart   Datasheet
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