IL12RB1

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The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YY2740 Anti-IL12RB1 (CBYY-I0336) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYY-I0336 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY2743 Anti-IL12RB1 (NYRmIL-12p75) h(41BB-CD3ζ) CAR, pCDCAR1 NYRmIL-12p75 Rat scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY2754 Anti-IL12RB1 (CBYY-I0475) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYY-I0475 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY2785 Anti-IL12RB1 (CBYY-I0695) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYY-I0695 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY2862 Anti-IL12RB1 (CBYY-I1894) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYY-I1894 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3107 Anti-IL12RB1 (CBYY-I0336) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYY-I0336 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3110 Anti-IL12RB1 (NYRmIL-12p75) h(CD28-CD3ζ) CAR, pCDCAR1 NYRmIL-12p75 Rat scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3121 Anti-IL12RB1 (CBYY-I0475) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYY-I0475 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3152 Anti-IL12RB1 (CBYY-I0695) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYY-I0695 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-YY3229 Anti-IL12RB1 (CBYY-I1894) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYY-I1894 Mouse scfv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-CQ7103 Anti-IL12RB1 (CBXC-0765) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Non-Human Primate CBXC-0765 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7583 Anti-IL12RB1 (CBXC-0765) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human, Non-Human Primate CBXC-0765 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7244 Anti-IL12RB1 (CBFYC-0210) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBFYC-0210 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY7245 Anti-IL12RB1 (CBFYC-0418) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYC-0418 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY8042 Anti-IL12RB1 (CBFYC-0210) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBFYC-0210 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY8043 Anti-IL12RB1 (CBFYC-0418) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYC-0418 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4646 Anti-IL12RB1 (CBWJC-3804) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBWJC-3804 Armenian Hamster scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4918 Anti-IL12RB1 (CBWJC-3804) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CBWJC-3804 Armenian Hamster scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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