IL19

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The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP816 IL19 (IL20RA Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL19-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP817 IL19 (IL20RB Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL19-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2216 IL19 (IL20RA Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL19-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2217 IL19 (IL20RB Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL19-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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