IL5

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This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP849 IL5 (CSF2RB Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL5-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP850 IL5 (IL5RA Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL5-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2249 IL5 (CSF2RB Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL5-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2250 IL5 (IL5RA Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL5-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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