IL6

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This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP851 IL6 (IL6R Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL6-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP852 IL6 (IL6ST Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL6-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2251 IL6 (IL6R Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL6-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2252 IL6 (IL6ST Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL6-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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