KNG1

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This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP885 KNG1 (BDKRB1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human KNG1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP886 KNG1 (BDKRB2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human KNG1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP887 KNG1 (GPR135 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human KNG1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2285 KNG1 (BDKRB1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human KNG1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2286 KNG1 (BDKRB2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human KNG1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2287 KNG1 (GPR135 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human KNG1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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