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KSR2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LY911 Anti-KSR2 (1G4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1G4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY912 Anti-KSR2 (2G12) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2G12 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY913 Anti-KSR2 (3F11) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3F11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY914 Anti-KSR2 (4H2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 4H2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY915 Anti-KSR2 (5C4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5C4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY916 Anti-KSR2 (5E9) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5E9 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY917 Anti-KSR2 (6C9) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6C9 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY918 Anti-KSR2 (6F12) h(41BB-CD3ζ) CAR, pCDCAR1 Human 6F12 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2551 Anti-KSR2(1G4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1G4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2552 Anti-KSR2(2G12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2G12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2553 Anti-KSR2(3F11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3F11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2554 Anti-KSR2(4H2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4H2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2555 Anti-KSR2(5C4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5C4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2556 Anti-KSR2(5E9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5E9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2557 Anti-KSR2(6C9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6C9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2558 Anti-KSR2(6F12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 6F12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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