L1 cell adhesion molecule (L1-CAM)

L1 cell adhesion molecule(L1-CAM), also known as L1, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1, is encoded by the L1CAM gene, which is a transmembrane protein member of the L1 protein family. By the expression in neural, hematopoietic and transformed epithelial cells, this neuronal cell adhesion molecule playing a role in cell migration, adhesion, neurite outgrowth, myelination and neuronal differentiation. L1-CAM expression promotes invasiveness of the tumor as well as chemoresistance, which is related to ovarian cancer, colon cancer, glioma, renal cell cancer, neuroblastoma, endometrial cancer, melanoma, pancreatic cancer.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC259 T cell First ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ195 T cell First CE7 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ196 T cell Second CE7 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ197 T cell Second CE7 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC305 CE7 Lentivirus First scFv (CE7)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC306 CE7 Lentivirus First scFv (CE7)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC307 CE7 Lentivirus First scFv (CE7)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC308 CE7 Lentivirus Second scFv (CE7)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC309 CE7 Lentivirus Second scFv (CE7)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC310 CE7 Lentivirus Second scFv (CE7)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC311 CE7 Lentivirus First scFv (CE7)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC312 CE7 Lentivirus First scFv (CE7)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC313 CE7 Lentivirus Second scFv (CE7)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC314 CE7 Lentivirus First scFv (CE7)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC315 CE7 Lentivirus Third scFv (CE7)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC316 CE7 Lentivirus Third scFv (CE7)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC885 CE7 Lentivirus First scFv (CE7)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC886 CE7 Lentivirus Second scFv (CE7)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC887 CE7 Lentivirus Second scFv (CE7)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

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Australia
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