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MCM3AP

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The minichromosome maintenance protein 3 is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY2063 Anti-MCM3AP (CBFYM-0605) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-0605 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2064 Anti-MCM3AP (CBFYM-1903) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-1903 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5316 Anti-MCM3AP (CBFYM-0605) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-0605 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5317 Anti-MCM3AP (CBFYM-1903) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-1903 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY565 Anti-MCM3AP (1H3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1H3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2205 Anti-MCM3AP(1H3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1H3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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