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MLH1

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The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY2290 Anti-MLH1 (CBFYM-0063) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-0063 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2291 Anti-MLH1 (CBFYM-0311) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-0311 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2292 Anti-MLH1 (CBFYM-0656) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-0656 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2293 Anti-MLH1 (CBFYM-2286) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2286 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2294 Anti-MLH1 (CBFYM-2287) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2287 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2295 Anti-MLH1 (CBFYM-2288) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2288 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2296 Anti-MLH1 (CBFYM-2289) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2289 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2297 Anti-MLH1 (CBFYM-2290) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2290 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2298 Anti-MLH1 (CBFYM-2291) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2291 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2299 Anti-MLH1 (CBFYM-2292) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYM-2292 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2300 Anti-MLH1 (CBFYM-2293) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Monkey CBFYM-2293 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY2301 Anti-MLH1 (CBFYM-2294) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Monkey CBFYM-2294 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5543 Anti-MLH1 (CBFYM-0063) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-0063 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5544 Anti-MLH1 (CBFYM-0311) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-0311 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5545 Anti-MLH1 (CBFYM-0656) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-0656 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5546 Anti-MLH1 (CBFYM-2286) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-2286 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5547 Anti-MLH1 (CBFYM-2287) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-2287 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5548 Anti-MLH1 (CBFYM-2288) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-2288 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5549 Anti-MLH1 (CBFYM-2289) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-2289 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY5550 Anti-MLH1 (CBFYM-2290) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYM-2290 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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