MUC2

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This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP151 MUC2 (AGR2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human MUC2-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1551 MUC2 (AGR2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human MUC2-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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