NOTCH2

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This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WJ4778 Anti-NOTCH2 (B6) h(41BB-CD3ζ) CAR, pCDCAR1 Human B6 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4779 Anti-NOTCH2 (D3) h(41BB-CD3ζ) CAR, pCDCAR1 Human D3 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4780 Anti-NOTCH2 (16F11) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse 16F11 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4781 Anti-NOTCH2 (59R5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 59R5 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4782 Anti-NOTCH2 (Tarextumab) h(41BB-CD3ζ) CAR, pCDCAR1 Human Tarextumab Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4783 Anti-NOTCH2 (59R1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 59R1 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4784 Anti-NOTCH2 (CBWJN-0064) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJN-0064 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4785 Anti-NOTCH2 (CBWJN-0084) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBWJN-0084 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4786 Anti-NOTCH2 (CBWJN-0100) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBWJN-0100 Hamster scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4787 Anti-NOTCH2 (CBWJN-0101) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse CBWJN-0101 Hamster scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4788 Anti-NOTCH2 (18H4L20) h(41BB-CD3ζ) CAR, pCDCAR1 Human 18H4L20 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4789 Anti-NOTCH2 (18HCLC) h(41BB-CD3ζ) CAR, pCDCAR1 Human 18HCLC Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4790 Anti-NOTCH2 (7H239) h(41BB-CD3ζ) CAR, pCDCAR1 Human 7H239 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4791 Anti-NOTCH2 (8A1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 8A1 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4792 Anti-NOTCH2 (D67C8) h(41BB-CD3ζ) CAR, pCDCAR1 Human D67C8 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4793 Anti-NOTCH2 (D76A6) h(41BB-CD3ζ) CAR, pCDCAR1 Human D76A6 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4794 Anti-NOTCH2 (CBWJN-0691) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJN-0691 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4795 Anti-NOTCH2 (NOD-15) h(41BB-CD3ζ) CAR, pCDCAR1 Human NOD-15 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ5050 Anti-NOTCH2 (B6) h(CD28-CD3ζ) CAR, pCDCAR1 Human B6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ5051 Anti-NOTCH2 (D3) h(CD28-CD3ζ) CAR, pCDCAR1 Human D3 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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