NPPB

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This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP963 NPPB (NPR1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human NPPB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP964 NPPB (NPR2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human NPPB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP965 NPPB (NPR3 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human NPPB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2363 NPPB (NPR1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human NPPB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2364 NPPB (NPR2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human NPPB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2365 NPPB (NPR3 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human NPPB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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