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NXF1

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This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WJ1856 Anti-NXF1 (53H8) h(41BB-CD3ζ) CAR, pCDCAR1 Human 53H8 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1857 Anti-NXF1 (D5X4G) h(41BB-CD3ζ) CAR, pCDCAR1 D5X4G Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1858 Anti-NXF1 (CBWJN-1632) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBWJN-1632 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1859 Anti-NXF1 (CBWJN-1633) h(41BB-CD3ζ) CAR, pCDCAR1 CBWJN-1633 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4148 Anti-NXF1 (53H8) h(CD28-CD3ζ) CAR, pCDCAR1 Human 53H8 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4149 Anti-NXF1 (D5X4G) h(CD28-CD3ζ) CAR, pCDCAR1 D5X4G Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4150 Anti-NXF1 (CBWJN-1632) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBWJN-1632 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ4151 Anti-NXF1 (CBWJN-1633) h(CD28-CD3ζ) CAR, pCDCAR1 CBWJN-1633 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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