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OAS1

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This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ1638 Anti-OAS1 (2D4) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2D4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1639 Anti-OAS1 (CBXO-0014) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXO-0014 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1640 Anti-OAS1 (CBXO-0015) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXO-0015 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1641 Anti-OAS1 (CBXO-0016) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXO-0016 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1642 Anti-OAS1 (CBXO-0331) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXO-0331 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5062 Anti-OAS1 (2D4) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2D4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5063 Anti-OAS1 (CBXO-0014) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXO-0014 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5064 Anti-OAS1 (CBXO-0015) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXO-0015 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5065 Anti-OAS1 (CBXO-0016) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXO-0016 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5066 Anti-OAS1 (CBXO-0331) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXO-0331 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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