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PA

Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. In addition of its function in viral transcription, PA also plays an essential role in viral RNA synthesis and promotes the formation of the trimeric polymerase complex.

Associated Disease
  • Influenza
  • TCR Vector Products
  • TCR Viral Particles
  • TCR Cell Products
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-C207Z Chimeric anti-PA T cell receptor (6218), pCDTCR1 IAV 6218 Chimeric SSLENFRAYV HLA-DB Lentiviral   Add to Cart   Datasheet
TCR-YC0811 Human anti-PA T cell receptor (BC8B), pCDTCR1 BC8B Human Phosphatidic acid human CD1b Lentiviral vector   Add to Cart   Datasheet
TCR-YC0812 Human anti-PA T cell receptor (PG10), pCDTCR1 PG10 Human 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt) human CD1b Lentiviral vector   Add to Cart   Datasheet
TCR-YC0813 Human anti-PA T cell receptor (PG90), pCDTCR1 PG90 Human 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt) human CD1b Lentiviral vector   Add to Cart   Datasheet
TCR-YF240 Mouse anti-PA T cell receptor (501), pCDTCR1 Virus 501 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF241 Mouse anti-PA T cell receptor (509), pCDTCR1 Virus 509 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF242 Mouse anti-PA T cell receptor (514), pCDTCR1 Virus 514 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF243 Mouse anti-PA T cell receptor (515), pCDTCR1 Virus 515 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF244 Mouse anti-PA T cell receptor (524), pCDTCR1 Virus 524 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF245 Mouse anti-PA T cell receptor (525), pCDTCR1 Virus 525 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF246 Mouse anti-PA T cell receptor (526), pCDTCR1 Virus 526 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF247 Mouse anti-PA T cell receptor (530), pCDTCR1 Virus 530 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF248 Mouse anti-PA T cell receptor (532), pCDTCR1 Virus 532 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF249 Mouse anti-PA T cell receptor (538), pCDTCR1 Virus 538 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF250 Mouse anti-PA T cell receptor (553), pCDTCR1 Virus 553 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF251 Mouse anti-PA T cell receptor (558), pCDTCR1 Virus 558 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF252 Mouse anti-PA T cell receptor (604), pCDTCR1 Virus 604 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF253 Mouse anti-PA T cell receptor (607), pCDTCR1 Virus 607 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF254 Mouse anti-PA T cell receptor (652), pCDTCR1 Virus 652 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF255 Mouse anti-PA T cell receptor (653), pCDTCR1 Virus 653 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF256 Mouse anti-PA T cell receptor (657), pCDTCR1 Virus 657 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF257 Mouse anti-PA T cell receptor (660), pCDTCR1 Virus 660 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF258 Mouse anti-PA T cell receptor (695), pCDTCR1 Virus 695 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF259 Mouse anti-PA T cell receptor (704), pCDTCR1 Virus 704 Mouse SSLENFRAYV H2-Db Lentiviral vector   Add to Cart   Datasheet
TCR-YF290 Human anti-PA T cell receptor (UC2), pCDTCR1 Virus UC2 Human FMYSDFHFI HLA-A*02:01 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP077 Mouse anti-PA T cell receptor (2893), pCDTCR1 Influenza A virus 2893 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP078 Mouse anti-PA T cell receptor (2892), pCDTCR1 Influenza A virus 2892 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP079 Mouse anti-PA T cell receptor (2896), pCDTCR1 Influenza A virus 2896 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP080 Mouse anti-PA T cell receptor (2895), pCDTCR1 Influenza A virus 2895 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP081 Mouse anti-PA T cell receptor (2898), pCDTCR1 Influenza A virus 2898 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP082 Mouse anti-PA T cell receptor (2890), pCDTCR1 Influenza A virus 2890 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP083 Mouse anti-PA T cell receptor (2894), pCDTCR1 Influenza A virus 2894 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP084 Mouse anti-PA T cell receptor (2897), pCDTCR1 Influenza A virus 2897 Mouse SSLENFRAYV HLA-A*68:02 Lentiviral vector   Add to Cart   Datasheet

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